What is transposition of the great arteries?

4 May 2021

It is a serious congenital heart condition in which the two main arteries carrying blood out of the heart, that is, the aorta and the pulmonary artery, are switched in position.

Transposition of the great arteries arises during pregnancy when the baby’s heart is developing. Its origin is unknown, but some conditions during pregnancy can contribute to its appearance, such as:

Alcoholism.
Diabetes.
Smoking.
Malnutrition.
Presence of viral diseases in the mother, such as rubella.

There are two types of transposition of the great arteries:

Dextro-transposition of the great vessels.
Levo-transposition of the great vessels.

Signs and symptoms Transposition of the great arteries

The symptoms can be detected during a routine ultrasound during pregnancy or after birth, such as:

Bluish skin tone.
Clubbing of fingers or toes.
Difficulty breathing.
Underweight.
Poor appetite.
Weak pulse.

Transposition of the great arteries risks and complications:

Heart block.
Lack of oxygen in the tissues.
Heart failure.
Heart valve problems.
Irregular heart rate.

Diagnosis and treatment Transposition of the great arteries

Once the doctor analyzes the symptoms and medical history, they will perform a physical examination of the baby to detect if there is a heart murmur and will order the following imaging studies to properly diagnose:

Cardiac ultrasound.
Electrocardiogram.
X-rays.

The main goal of treatment is to make oxygenated blood mix with low-oxygen blood through:

Medication.
Cardiac catheterization.
Corrective surgery after birth.

At the Cardiovascular Center, we offer you a wide range of prevention, diagnosis, timely treatment, and follow-up services to take care of you through a comprehensive and multidisciplinary care model. Come to us, we want to hear your heart.

Related centers and departments Transposition of the great arteries

Cardiovascular Center
High Specialty Surgery Center
Radiology and Molecular Imaging
Clinical Laboratory

Fuentes:

fundaciondelcorazon.com
heart.org
stanfordchildrens.org
cardiopatiascongenitas.net
cincinnatichildrens.org
mayoclinic.org
medlineplus.gov
texasheart.org
medigraphic.org
García-Hernández HA, Castelló-Magallanes RJ, Lupercio-Macías SM, et al. Corrección temprana de transposición de grandes vasos: reporte de un caso y revisión de la literatura. Rev Med MD. 2016;7.8(4):280-284.
Ley VL, Clemades MAM, Satorre YJA. Transposicion de grandes arterias diagnosticada en un feto de 22 semanas. CorSalud. 2012;4(4):294-295.
Seijas CJA, Naranjo UA, Marcano SL, et al. Entrenamiento ventricular izquierdo previo a la corrección anatómica en un lactante con transposición de grandes vasos. Rev Cubana Cardiol Cir Cardiovasc. 2014;20(1):.

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The dissemination of the content of this material is for informational purposes only and does not replace, under any circumstance or condition, a consultation with a specialist doctor, for which the Saludora Medical Center is not responsible for the different use that may be given to it. If you require more information related to the subject, we suggest you contact the specialist doctor you trust directly.

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Comparison of COVID-19 vaccines

Pfizer-
BioNTech

Pfizer-BioNTech

What is its effectiveness and what does it refer to?

Vaccine type: mRNA
Effectiveness: 95% after the second dose in the prevention of symptomatic COVID-19.

No Does not contain egg, latex, or preservatives.

How many doses are needed?
Two doses are needed, at least 21 days apart (or up to six weeks apart, if necessary).

Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 16 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine such as polyethylene glycol (PEG) or polysorbate.

What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, muscle pain, chills, joint pain, fever, nausea, malaise, and swollen lymph nodes.

How long will it take for me to be protected and what does it protect me from?
After 14 days of having the complete scheme (after the administration of the 2nd dose), the protection period is still under study. It protects us from serious COVID-19 or requiring hospitalization.

Moderna

What is its effectiveness and what does it refer to?

Vaccine type: mRNA
Effectiveness: 94.5% after the second dose in the prevention of symptomatic COVID-19.

Does not contain egg, latex, or preservatives.

How many doses are needed?
Two doses are needed, at least 28 days apart (or up to six weeks apart, if necessary).

Who should or shouldn’t get the vaccine?
People who should receive the vaccine are those over 18 years old.
People who should not receive the vaccine are those who have a history of anaphylactic shock (severe allergy) or who are allergic to any component of this vaccine.

What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, muscle pain, chills, joint pain, fever, nausea, and swollen lymph nodes in the arm in which you received the injection.

Janssen/
Johnson
& Johnson

Janssen/ Johnson & Johnson

What is its effectiveness and what does it refer to?

Vector-based vaccine.
Effectiveness: 72.0% in the prevention of symptomatic COVID-19.
85% in the prevention of severe COVID-19.

Does not contain egg, latex, or preservatives./strong>

How many doses are needed?
Only one dose in needed.

What are the possible side effects of the vaccine?
Pain where the injection was given, headache, fatigue, muscle pain, chills, fever, and nausea.

How long will it take for me to be protected and what does it protect me from?
After 28 days of having the complete scheme (the last dose applied), the protection period is still under study. It protects us from 85% serious COVID-19 or requiring hospitalization.

AstraZeneca
and
Oxford
University

AstraZeneca and Oxford University

What is its effectiveness and what does it refer to?

Adenovirus vector-based vaccine.
Effectiveness: 82% after the second dose in the prevention of symptomatic COVID-19.

How many doses are needed?
Two doses are needed, at least 56 days apart (or up to 84 days apart, if necessary).

What are the possible side effects of the vaccine?
Pain where the injection was given, fatigue, headache, myalgia, arthralgia, and fever, which were mild to moderate in intensity and disappeared within 48 hours of vaccination.

Sputnik V

What is its effectiveness and what does it refer to?

Adenovirus vector-based vaccine.
Effectiveness: 92% after the second dose in the prevention of symptomatic COVID-19.

How many doses are needed?
Two doses are needed, at least 21 days apart (or up to six weeks apart, if necessary).

What is transposition of the great arteries?

Signs and symptoms Transposition of the great arteries

Diagnosis and treatment Transposition of the great arteries

Related centers and departments Transposition of the great arteries

Fuentes:

Index

Specialist in Transposition of the great arteries